To the best of our knowledge, however, no research has investigated the validity of MoCA index scores in comparison with conventional neuropsychological tests. 10Īs with the studies described above, many researchers have paid attention to the MoCA index scores. Another study used the MoCA index score for detection of cognitive decline due to neurodegenerative diseases such as AD as well as for confirming the therapeutic effect of alcoholic cognitive decline. 9 showed that memory and orientation index scores were lowest in the AD group, whereas language and attention index scores were lowest in primary progressive aphasia (PPA). Some studies were conducted to confirm the differences between clinical groups through the MoCA index score.

In distinguishing healthy individuals from MCI, the total MoCA score had stronger incremental validity than the index scores, and a combined index score was more informative than the individual index scores. 8 investigated effect sizes of the MoCA total and index scores in differentiating individuals with healthy cognition from those with MCI or AD. 7 found that MoCA memory index score was better at discriminating amnestic MCI (aMCI) from normal cognition than the paragraph recall. They reported that 90.5% of patients with both scores below the cutoff for impairment–total score (20/30 points) and memory index score (7/15 points)–converted to AD, whereas 74.5% converted when one of two scores was below the cutoff. In their study, In their study, they produced cut-off scores that predicted MCI conversion to AD. 6 proposed MoCA index scores for the six cognitive domains comprising subtests of the MoCA: orientation, attention, language, visuospatial function, memory, and executive function. 1 However, it has also been useful for assessing vascular cognitive impairment (VCI) 2, 3 and cognitive impairment in Parkinson's disease 4 since it proportionally involves many subtests for assessing frontal and executive function.

It was originally developed for the screening of mild cognitive impairment (MCI), which converts to Alzheimer's disease (AD). The Montreal Cognitive Assessment (MoCA) is a cognitive screening test used internationally.

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